Machado Marcel Cerqueira Cesar, Fonseca Gilton Marques, de Meirelles Luciana Rodrigues, Siqueira Luiz Tenorio de Brito, Katz Betina, Jukemura José
Department of Clinical Emergencies, University of São Paulo School of Medicine, São Paulo 01409-001, Brazil.
Digestive Surgery Division, Department of Gastroenterology, University of São Paulo School of Medicine, São Paulo 05403-900, Brazil.
Pancreatology. 2015 Nov-Dec;15(6):708-12. doi: 10.1016/j.pan.2015.09.009. Epub 2015 Oct 3.
Cystic neoplasms account for approximately 10-20% of all pancreatic cysts and 1% of pancreatic cancers. Serous cystadenomas are considered benign tumors with almost no malignant potential, and thus the management is typically only observation with serial imaging. According to the current World Health Organization classification, cases with distant metastases are defined as serous cystadenocarcinomas. To date, only 17 such cases with concomitant synchronous or metachronous liver metastasis have been described in the literature, and eight of these reports described treatment of secondary liver lesions. This report describes the first case of synchronous resection of pancreatic serous cystadenocarcinoma and liver metastasis in a 56-year-old female patient. The patient is currently well after 30 months of follow-up with no tumor recurrence or new metastatic liver nodules based on magnetic resonance imaging.
囊性肿瘤约占所有胰腺囊肿的10%-20%，占胰腺癌的1%。浆液性囊腺瘤被认为是良性肿瘤，几乎没有恶变潜能，因此其治疗通常仅为定期影像学观察。根据世界卫生组织目前的分类，发生远处转移的病例被定义为浆液性囊腺癌。迄今为止，文献中仅描述了17例伴有同步或异时性肝转移的此类病例，其中8篇报告描述了继发性肝病变的治疗。本报告描述了首例56岁女性患者同步切除胰腺浆液性囊腺癌和肝转移灶的病例。该患者在随访30个月后情况良好，根据磁共振成像检查，无肿瘤复发或新的肝转移结节。
