Gondim Jackson, Ramos Francisco, Azevedo Jorge, Carrero Fernando Porto, Tella Oswaldo Inácio
Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.
Arq Neuropsiquiatr. 2002 Jun;60(2-A):303-7. doi: 10.1590/s0004-282x2002000200024.
Esthesioneuroblatoma (ENB) is a rare tumor arising from the olfactory epithelium of the nasal vault which frequently invades the cranial base, cranial vault and orbit. ENB has a bimodal age distribution between 11 and 20 years and between 51 and 60 years. ENB accounts for approximately 1 to 5% of intranasal cancers and no consensus has been reached regarding treatment of this tumor. We report on a 66 year old female patient with a Kadish stage C tumor with frontal lobe invasion submitted a total craniofacial resection with a combined head neck and neurosurgeon team. The purpose of this study is to analyze the natural history, treatment and prognosis of this tumor, based on the literature review.
嗅神经母细胞瘤（ENB）是一种罕见的肿瘤，起源于鼻腔顶部的嗅上皮，常侵犯颅底、颅顶和眼眶。ENB的年龄分布呈双峰型，分别在11至20岁以及51至60岁之间。ENB约占鼻内癌的1%至5%，对于该肿瘤的治疗尚未达成共识。我们报告了一名66岁的女性患者，患有卡迪什C期肿瘤并侵犯额叶，由头颈外科和神经外科联合团队进行了全颅面切除术。本研究的目的是基于文献综述分析该肿瘤的自然病程、治疗及预后。
