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经外照射放疗治疗的嗅神经母细胞瘤。病例报告。

Esthesioneuroblastoma treated with external radiotherapy. Case report.

作者信息

Tramacere F, Bambace S, De Luca M C, Castagna R, Francavilla M C, Leone A, Monastero S, Fucilli F, Pili G, Portaluri M

机构信息

Radiotherapy Unit, AUSL BR1, Perrino Hospital, Brindisi.

出版信息

Acta Otorhinolaryngol Ital. 2008 Aug;28(4):215-7.

Abstract

Esthesioneuroblastoma is a rare tumour arising from the olfactory epithelium of the nasal vault which frequently invades the cranial base and orbit. Esthesioneuroblastoma has a bimodal age distribution between 11 and 20 years and between 51 and 60 years. Esthesioneuroblastoma accounts for approximately 1-5% of intranasal cancers. The case is reported of a 79-year-old female patient with a Kadish stage C tumour with a one-year history of headache, nasal obstruction, anosmia, rhinorrhoea and epistaxis. Aim of this study is to analyse the natural history, treatment and prognosis of this tumour, based on a review of the literature.

摘要

嗅神经母细胞瘤是一种起源于鼻腔顶部嗅上皮的罕见肿瘤,常侵犯颅底和眼眶。嗅神经母细胞瘤的发病年龄呈双峰分布,分别在11至20岁以及51至60岁之间。嗅神经母细胞瘤约占鼻内癌的1%至5%。本文报道了一例79岁女性患者,患有卡迪什C期肿瘤,有一年的头痛、鼻塞、嗅觉丧失、鼻漏和鼻出血病史。本研究的目的是在文献回顾的基础上,分析该肿瘤的自然病史、治疗方法和预后。

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本文引用的文献

3
Esthesioneuroblastoma: case report.嗅神经母细胞瘤:病例报告。
Arq Neuropsiquiatr. 2002 Jun;60(2-A):303-7. doi: 10.1590/s0004-282x2002000200024.
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The role of stereotactically guided conformal radiotherapy for local tumor control of esthesioneuroblastoma.
Strahlenther Onkol. 2002 Apr;178(4):187-91. doi: 10.1007/s00066-002-0894-y.
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Esthesioneuroblastoma: prognosis and management.嗅神经母细胞瘤:预后与治疗
Neurosurgery. 1993 May;32(5):706-14; discussion 714-5. doi: 10.1227/00006123-199305000-00002.
9
Olfactory neuroblastoma. Biologic and clinical behavior.嗅神经母细胞瘤。生物学和临床行为。
Arch Otolaryngol. 1983 Dec;109(12):797-802. doi: 10.1001/archotol.1983.00800260019005.
10

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