Tramacere F, Bambace S, De Luca M C, Castagna R, Francavilla M C, Leone A, Monastero S, Fucilli F, Pili G, Portaluri M
Radiotherapy Unit, AUSL BR1, Perrino Hospital, Brindisi.
Acta Otorhinolaryngol Ital. 2008 Aug;28(4):215-7.
Esthesioneuroblastoma is a rare tumour arising from the olfactory epithelium of the nasal vault which frequently invades the cranial base and orbit. Esthesioneuroblastoma has a bimodal age distribution between 11 and 20 years and between 51 and 60 years. Esthesioneuroblastoma accounts for approximately 1-5% of intranasal cancers. The case is reported of a 79-year-old female patient with a Kadish stage C tumour with a one-year history of headache, nasal obstruction, anosmia, rhinorrhoea and epistaxis. Aim of this study is to analyse the natural history, treatment and prognosis of this tumour, based on a review of the literature.
嗅神经母细胞瘤是一种起源于鼻腔顶部嗅上皮的罕见肿瘤，常侵犯颅底和眼眶。嗅神经母细胞瘤的发病年龄呈双峰分布，分别在11至20岁以及51至60岁之间。嗅神经母细胞瘤约占鼻内癌的1%至5%。本文报道了一例79岁女性患者，患有卡迪什C期肿瘤，有一年的头痛、鼻塞、嗅觉丧失、鼻漏和鼻出血病史。本研究的目的是在文献回顾的基础上，分析该肿瘤的自然病史、治疗方法和预后。
