Oostenbrink Rianne, Maas Mariëlle, Moons Karel G M, Moll Henriëtte A
Sophia Children's Hospital, University Hospital Rotterdam, The Netherlands.
Scand J Infect Dis. 2002;34(5):379-82. doi: 10.1080/00365540110080179.
The neurological outcome of bacterial meningitis in children was evaluated retrospectively. Data were obtained from a large study on children aged between 1 month and 15 y who initially visited the emergency department of Sophia Children's Hospital, Rotterdam, The Netherlands with meningeal signs. This study presents data from 103 patients in whom bacterial meningitis was diagnosed. Neisseria meningitidis was the dominant pathogen of meningitis. We found a 2% case-fatality rate in children with bacterial meningitis and a 13% rate of sequelae among survivors: 7% hearing impairment and 7% neurological sequelae. Children with bacterial meningitis caused by Streptococcus pneumoniae and those with acute focal neurological symptoms tended to have the worst prognosis.
我们对儿童细菌性脑膜炎的神经学转归进行了回顾性评估。数据来自一项针对1个月至15岁儿童的大型研究,这些儿童最初因脑膜刺激征前往荷兰鹿特丹索菲亚儿童医院急诊科就诊。本研究展示了103例确诊为细菌性脑膜炎患者的数据。脑膜炎奈瑟菌是脑膜炎的主要病原体。我们发现细菌性脑膜炎患儿的病死率为2%,幸存者中有13%出现后遗症:7%听力受损,7%出现神经后遗症。由肺炎链球菌引起细菌性脑膜炎的患儿以及有急性局灶性神经症状的患儿预后往往最差。