Servaes Petra, Prins Judith, Verhagen Stans, Bleijenberg Gijs
Netherlands Fatigue Research Group, Department of Medical Psychology (118), University Medical Centre Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
J Psychosom Res. 2002 Jun;52(6):453-9. doi: 10.1016/s0022-3999(02)00300-8.
Fatigue is investigated in 57 severely fatigued disease-free breast cancer patients and in 57 gender- and age-matched patients with chronic fatigue syndrome (CFS) using multidimensional and multimethod assessment. A comparison between these groups of patients is important to determine whether a cognitive behavioural intervention to reduce fatigue in CFS patients would be appropriate as well for severely fatigued disease-free breast cancer patients.
Measurement included computerised questionnaires and a standardised neuropsychological test. Furthermore, patients filled out a daily Self-Observation List (SOL) and wore an actometer during a period of 12 days.
In comparison to severely fatigued disease-free breast cancer patients, CFS patients score more problematic with regard to the level of fatigue, functional impairment, physical activity, pain and self-efficacy. However, a subgroup of severely fatigued disease-free breast cancer patients reports the same amount of problems as CFS patients with regard to psychological well-being, sleep and concentration. Finally, CFS patients and severely fatigued breast cancer patients score equal on measures of social support.
There seem to be some similarities but also many differences between severely fatigued breast cancer survivors and females with CFS. Therefore, cognitive behaviour therapy (CBT) to reduce fatigue after treatment for cancer should also differ in certain aspects from cognitive behaviour therapy as it has been developed for patients with CFS.
采用多维度和多方法评估，对57名无疾病的重度疲劳乳腺癌患者以及57名性别和年龄匹配的慢性疲劳综合征（CFS）患者的疲劳情况进行调查。比较这两组患者对于确定针对CFS患者减轻疲劳的认知行为干预是否也适用于无疾病的重度疲劳乳腺癌患者很重要。
测量包括计算机化问卷和标准化神经心理测试。此外，患者填写每日自我观察清单（SOL），并在12天内佩戴活动计。
与无疾病的重度疲劳乳腺癌患者相比，CFS患者在疲劳程度、功能损害、身体活动、疼痛和自我效能方面得分更高。然而，一部分无疾病的重度疲劳乳腺癌患者在心理健康、睡眠和注意力方面报告的问题与CFS患者相同。最后，CFS患者和重度疲劳乳腺癌患者在社会支持测量方面得分相等。
重度疲劳的乳腺癌幸存者和患有CFS的女性之间似乎存在一些相似之处，但也有许多差异。因此，癌症治疗后减轻疲劳的认知行为疗法（CBT）在某些方面也应与为CFS患者开发的认知行为疗法有所不同。
