Gruber P C, Whittam L R, du Vivier A
King's College Hospital, London, UK.
Clin Exp Dermatol. 2002 May;27(3):188-91. doi: 10.1046/j.1365-2230.2002.00994.x.
We report an unusual case of tuberculosis verrucosa cutis on the plantar aspect of the foot that had been present for more than 40 years in a 62-year-old Indian man. He had a grade IV positive Heaf test and a normal chest radiograph. Mycobacterium tuberculosis was successfully cultured from the third biopsy taken from the lesion. This case demonstrates the indolent nature of the lesion and stresses the importance of taking adequate biopsies for microbiological culture when there is a high index of suspicion for M. tuberculosis. The diagnosis of tuberculosis verrucosa cutis should be based on history and evolution of the disease, cardinal morphological features and histopathological characteristics. Response to anti-tuberculosis drugs may be of assistance.
我们报告了一例罕见的足部跖侧疣状皮肤结核病例，该病例出现在一名62岁的印度男性身上，病程超过40年。他的希夫试验呈IV级阳性，胸部X光片正常。从病变部位的第三次活检中成功培养出结核分枝杆菌。该病例显示了病变的惰性，并强调当高度怀疑结核分枝杆菌时，进行充分活检以进行微生物培养的重要性。疣状皮肤结核的诊断应基于疾病的病史和演变、主要形态特征以及组织病理学特征。对抗结核药物的反应可能会有所帮助。
