Dermatology and Venereology Department, Faculty of Medicine, Hasanuddin University, Hasanuddin University Hospital, Makassar, South Sulawesi, Indonesia.
Pan Afr Med J. 2020 Nov 4;37:216. doi: 10.11604/pamj.2020.37.216.26531. eCollection 2020.
Tuberculosis verrucosa cutis is a paucibacillary form of cutaneous tuberculosis that often occurs in sensitized immunocompetent individuals due to exogenous reinfection. The diagnosis is often difficult because the clinical features are often not typical and acid-fast staining test often shows negative results. Therapeutic trial with antituberculosis therapy is justified if there is strong clinical suspicion in which diagnosis can be made based on the therapeutic response. We report a 46-year-old male with erythematous verrucous plaque on the right knee and crusted erythematous plaque on the left dorsal foot that had been present for 20 years. There were neither history of previous trauma nor tuberculosis treatment. Histopathology, culture, polymerase chain reaction (PCR), Mantoux test, and chest radiograph were negative for cutaneous tuberculosis. Gamma release interferon assay showed positive result. The patient was given category 1 antituberculosis treatment and showed improvement after three weeks. Treatment was continued for 6 months and the lesion significantly regressed.
寻常狼疮是一种少菌型皮肤结核，常发生于对外来再感染具有敏感性的免疫功能正常个体。由于临床表现通常不典型，抗酸染色试验常为阴性，因此诊断往往较为困难。如果临床高度怀疑，且抗结核治疗有明确的疗效，可进行诊断性治疗。我们报告了 1 例 46 岁男性，其右膝部有红色疣状斑块，左背部有结痂性红斑，病史 20 年。患者无既往外伤史，也未进行过结核病治疗。皮肤结核的组织病理学、培养、聚合酶链反应（PCR）、曼图试验和胸部 X 线检查均为阴性。γ干扰素释放试验结果阳性。该患者接受了 1 类抗结核治疗，3 周后病情改善。治疗持续 6 个月后，皮损明显消退。
