Bauzá A, Redondo P, Idoate M A
Department of Dermatology, University Clinic of Navarra, Pamplona, Spain.
Clin Exp Dermatol. 2002 May;27(3):199-201. doi: 10.1046/j.1365-2230.2002.01006.x.
Cutaneous metastases from internal malignancies or primary skin cancers are uncommon, and a zosteriform pattern is very rare. Histologically, these cutaneous metastases usually appear as malignant epithelial cells located throughout the dermis or subcutaneous fat and without connection to the overlying epidermis. The presence of melanocytes in such lesions is atypical. Moreover, although zosteriform cutaneous metastases of cutaneous squamous cell carcinoma have previously been described in immunosuppressed patients, they have not been reported in immunocompetent patients. We report an unusual case of a woman with cutaneous hyperchromic zosteriform metastases, clinically mimicking a metastatic melanoma but appearing histologically as epidermotropic and pigmented metastases of a cutaneous squamous cell carcinoma.
来自内部恶性肿瘤或原发性皮肤癌的皮肤转移并不常见，而带状分布模式则极为罕见。从组织学上看，这些皮肤转移瘤通常表现为位于整个真皮层或皮下脂肪中的恶性上皮细胞，且与上方的表皮无连接。此类病变中存在黑素细胞是非典型的。此外，尽管此前已在免疫抑制患者中描述过皮肤鳞状细胞癌的带状皮肤转移，但在免疫功能正常的患者中尚未见报道。我们报告了一例不寻常的病例，一名女性患有皮肤色素沉着性带状转移瘤，临床上酷似转移性黑色素瘤，但组织学表现为皮肤鳞状细胞癌的亲表皮性和色素性转移瘤。
