Local rupture of the veins by fracture. Compression and local spiral thrombi. 2. Failure of the venous pump at the ankle joint due to immobilization. 3. Failure of the pump in the calf muscles, leading to propagation of thrombi in the venae gastrocnemiae and in the veins of the soleus muscle, frequently with varicosity. 4. In 22 percent of left-sided fractures a venous spur is found in the left V. iliaca com.; increased likelihood of thrombosis in left leg in case of stasis due to immobilization.