[Effectiveness of different strategies of vaccine prophylaxis for poliomyelitis in the Ukraine].

The use of oral poliomyelitis vaccine (OPV) in Ukraine permitted achieving absence of cases poliomyelitis caused by "wild" polioviruses. All registered in recent years cases of poliomyelitis are associated with vaccination. In quest of optimal schemes of vaccination the study was made of the immunity tension in children with making use of an inactivated poliomyelitis vaccine (IPV). IPV + IPV + IPV/IVP + OPV + OPV schemes of immunization are more effective as compared to the conventional scheme of immunization (OPV + OPV + OPV). These have been shown to provide both individual and collective defence against type 3 poliovirus and to reduce the risk for development of the vaccine-associated poliomyelitis.