Moĭseieva H V, Zadorozhna V I
Lik Sprava. 2002(2):85-8.
The use of oral poliomyelitis vaccine (OPV) in Ukraine permitted achieving absence of cases poliomyelitis caused by "wild" polioviruses. All registered in recent years cases of poliomyelitis are associated with vaccination. In quest of optimal schemes of vaccination the study was made of the immunity tension in children with making use of an inactivated poliomyelitis vaccine (IPV). IPV + IPV + IPV/IVP + OPV + OPV schemes of immunization are more effective as compared to the conventional scheme of immunization (OPV + OPV + OPV). These have been shown to provide both individual and collective defence against type 3 poliovirus and to reduce the risk for development of the vaccine-associated poliomyelitis.
在乌克兰使用口服脊髓灰质炎疫苗（OPV）使得由“野生”脊髓灰质炎病毒引起的脊髓灰质炎病例得以消除。近年来所有登记的脊髓灰质炎病例都与疫苗接种有关。为了寻求最佳的疫苗接种方案，利用灭活脊髓灰质炎疫苗（IPV）对儿童的免疫强度进行了研究。与传统的免疫接种方案（OPV+OPV+OPV）相比，IPV+IPV+IPV/IVP+OPV+OPV免疫方案更有效。这些方案已被证明既能提供针对3型脊髓灰质炎病毒的个体和集体防御，又能降低疫苗相关脊髓灰质炎的发病风险。
