Ongenae Katia, Van De Kerckhove Marianne, Naeyaert Jean-Marie
Department of Dermatology, Ghent University, Belgium.
Dermatology. 2002;204(4):348-50. doi: 10.1159/000063383.
We present a case of Bowen's disease of the nail bed in a 60-year-old male. This case should remind us to biopsy any chronic lesion of the nail in order to reduce the delay in diagnosis. Indeed Bowen's disease of the nail unit often presents as a clinically misleading 'benign' lesion. Early diagnosis is important as this precancerous lesion appears to have a more aggressive behavior when it affects the nail unit. Bowen's disease of the nail is therefore considered as a squamous cell carcinoma, and both entities are grouped under the term 'epidermoid carcinoma'. Surgical excision is the first treatment option for those tumors without bone involvement. Our patient was treated with Mohs' micrographic surgery which is considered the ideal surgical treatment as it ensures a complete eradication of the tumor in over 90% of the cases but also maximally preserves normal tissue and function. This case illustrates the challenge of Mohs' surgery on the nail unit due to its particular anatomy and histology.
我们报告一例60岁男性甲床鲍恩病的病例。该病例应提醒我们,对于任何甲部慢性病变都应进行活检,以减少诊断延误。实际上,甲单位的鲍恩病常表现为临床上具有误导性的“良性”病变。早期诊断很重要,因为这种癌前病变在累及甲单位时似乎具有更侵袭性的行为。因此,甲部鲍恩病被视为鳞状细胞癌,这两种实体都归在“表皮样癌”这一术语下。对于那些未累及骨骼的肿瘤,手术切除是首选治疗方法。我们的患者接受了莫氏显微外科手术治疗,该手术被认为是理想的手术治疗方式,因为它能确保在超过90%的病例中完全切除肿瘤,同时最大程度地保留正常组织和功能。该病例说明了由于甲单位特殊的解剖结构和组织学特点,莫氏手术在其上实施所面临的挑战。