Alvarez Gabriella, Kha Connie, Selim M Angelica, Fresco Amber
School of Medicine, Duke University, Durham, NC, USA.
Department of Dermatology, Duke University Hospital, Durham, NC, USA.
Skin Appendage Disord. 2023 Aug;9(4):296-299. doi: 10.1159/000530470. Epub 2023 Jun 2.
Onychocytic matricoma (OCM) is a benign acanthoma of the nail matrix that presents with longitudinal melanonychia and nail thickening. Only 18 previously reported cases of OCM are in the literature since it was first described in 2012.
The purpose of this case report was to report a unique presentation of OCM in the toenail of a Black patient as well as to review the clinical presentation, histologic features, and management of this rare entity. Previously described cases presented on the fingernails and were predominantly in white males.
OCM is a benign entity that may mimic a nail unit melanoma or squamous cell carcinoma especially when pachyonychia is present. Despite some clinical clues to suggest a diagnosis of OCM, a nail matrix biopsy is often required to rule out malignancy.
甲母质细胞痣（OCM）是一种甲母质的良性棘皮瘤，表现为纵向黑甲和指甲增厚。自2012年首次描述以来，文献中仅报道了18例OCM病例。
本病例报告的目的是报告一名黑人患者趾甲中OCM的独特表现，并回顾这种罕见疾病的临床表现、组织学特征和治疗方法。先前描述的病例发生在指甲上，主要为白人男性。
OCM是一种良性疾病，尤其在出现厚甲时可能会模仿甲单位黑色素瘤或鳞状细胞癌。尽管有一些临床线索提示OCM的诊断，但通常仍需要进行甲母质活检以排除恶性肿瘤。
