[通草与小通草多糖抗氧化作用的实验研究]
[Experimental studies on antioxidative effect of tongcao and xiao-tongcao polysaccharides].
作者信息
Zeng N, Shen Y, Jia M, Zhang Y, Wei Y, Ma Y
机构信息
Chengdu University of TCM, Chengdu 610075.
出版信息
Zhongguo Zhong Yao Za Zhi. 1999 Jan;24(1):46-8, inside back cover.
OBJECTIVE
To observe the antioxidative effect of four kinds of Tongcao and Xiao-Tongcao polysaccharides.
METHOD
Aged mice (nine months) were abdominal administrated with four kinds of polysaccharides (Tongtuomu, Ximashanjingjiehua, Xinanxiuqiu, Ditanghua) at dosages of 160 mg/kg and 80 mg/kg for 45 days.
RESULT
Four kinds of polysaccharides could obviously decrease the content of serum and liver lipoperoxide(LPO) as well as the content of lipofuscin(LF) in brain and cardiac muscle of aged mice, and also increase the activity of superoxide dismutase(SOD) of red cells in aged mice.
CONCLUSION
The polysaccharide components of Tongtuomu and three kinds of Xiao-Tongcao have antioxidative effect, suggesting that these substances have antiageing function.
目的
观察四种通草及小通草多糖的抗氧化作用。
方法
将九个月龄的老龄小鼠分别以160mg/kg和80mg/kg的剂量腹腔注射四种多糖（通脱木、喜马拉雅旌节花、西南绣球、地桃花），持续45天。
结果
四种多糖可显著降低老龄小鼠血清和肝脏中脂质过氧化物（LPO）的含量，以及脑和心肌中脂褐素（LF）的含量，还可提高老龄小鼠红细胞中超氧化物歧化酶（SOD）的活性。
结论
通脱木及三种小通草的多糖成分具有抗氧化作用，提示这些物质具有抗衰老功能。
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