Zhang Jian, Xu Yun-Ming, Wang Wei-Min, Liu Yan-Qing
Medical School of Yangzhou University, Yangzhou 225001, China.
Zhongguo Zhong Yao Za Zhi. 2006 Sep;31(18):1514-6.
To study the anti-tumor activity of extractive from Celastrus orbiculatus in vivo.
Mice bearing transplanted tumor S180 and Heps were used to study the effects of acetoacetate and n-butanol extractive from C. orbiculatus. The changes in serum contents of SOD and malondialdehyde (MDA) content were assayed.
Acetoacetate and n-butanol extractive from C. orbiculatus significantly inhibited the growth of S180 and Heps tumor in mice. SOD content was obviously increased, MDA content obviously decreased in the serum after extractive treatment.
Acetoacetate and n-butanol extractive from C. orbiculatus have anti-tumor effects and anti-oxidative capacity.
研究南蛇藤提取物的体内抗肿瘤活性。
采用移植瘤S180和Heps小鼠模型，研究南蛇藤乙酸乙酯提取物和正丁醇提取物的作用。检测血清中超氧化物歧化酶（SOD）含量及丙二醛（MDA）含量的变化。
南蛇藤乙酸乙酯提取物和正丁醇提取物显著抑制小鼠S180和Heps肿瘤生长。提取物处理后血清中SOD含量明显升高，MDA含量明显降低。
南蛇藤乙酸乙酯提取物和正丁醇提取物具有抗肿瘤作用及抗氧化能力。
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