Reiter R J, Blask D E, Vaughan M K
Neuroendocrinology. 1975;19(1):72-80. doi: 10.1159/000122427.
Blinding and anosmia in male rats is followed by retarded bodily development, reduced weights of the gonads and adnexa, and depressed levels of pituitary luteinizing hormone and prolactin. The effects of dual sensory deprivation are negated, for the most part, by either pinealectomy or the weekly subcutaneous implantation of melatonin (in beeswax). This is the first report that melatonin negates the antigonadotrophic influence of the rat pineal gland.
雄性大鼠失明和嗅觉缺失后,身体发育迟缓,性腺及附件重量减轻,垂体促黄体生成素和催乳素水平降低。松果体切除或每周皮下植入褪黑素(于蜂蜡中)在很大程度上可消除双重感觉剥夺的影响。这是关于褪黑素可消除大鼠松果体抗促性腺激素影响的首份报告。