Hamre Merlin R, Chuba Paul, Bakhshi Samee, Thomas Ron, Severson Richard K
Department of Pediatrics and Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA.
Pediatr Hematol Oncol. 2002 Jul-Aug;19(5):309-17. doi: 10.1080/08880010290057327.
Using population-based data from the Surveillance Epidemiology and End Results Program of the National Cancer Institute, melanoma occurring during childhood was evaluated. Compared to adult cases of melanoma, childhood cases had a higher proportion of females (61%) and non-Caucasians (6.5%). The incidence of melanoma increased 85% among 15- to 19-year-olds from 1973 to 1996. Incidence for 15- to 19-year-olds was higher in southern (23.9/million) than northern registries (14.5/million). Non-Caucasians had 3-30% of the cases expected compared to Caucasians. Overall survival of children/adolescents with melanoma was 89% and 79% at 5 and 20 years postdiagnosis, respectively. The majority of deaths were directly attributed to melanoma (72%).
利用美国国立癌症研究所监测、流行病学和最终结果计划中的基于人群的数据,对儿童期发生的黑色素瘤进行了评估。与成人黑色素瘤病例相比,儿童病例中女性比例更高(61%),非白种人比例更高(6.5%)。1973年至1996年期间,15至19岁青少年的黑色素瘤发病率增加了85%。南部地区(每百万人口中23.9例)15至19岁青少年的发病率高于北部登记处(每百万人口中14.5例)。与白种人相比,非白种人的病例数占预期病例数的3%至30%。黑色素瘤患儿/青少年诊断后5年和20年的总生存率分别为89%和79%。大多数死亡直接归因于黑色素瘤(72%)。