Saladin Michael E, Drobes David J, Coffey Scott F, Libet Julian M
College of Health Professions and Center for Drug and Alcohol Programs, Medical University of South Carolina, Rehabilitation Sciences Department, Charleston 29425, USA.
Psychol Addict Behav. 2002 Jun;16(2):98-105. doi: 10.1037//0893-164x.16.2.98.
This study investigated the human eyeblink startle reflex as a measure of alcohol cue reactivity. Alcohol-dependent participants early (n = 36) and late (n = 34) in abstinence received presentations of alcohol and water cues. Consistent with previous research, greater salivation and higher ratings of urge to drink occurred in response to the alcohol cues. Differential salivary and urge responding to alcohol versus water cues did not vary as a function of abstinence duration. Of special interest was the finding that startle response magnitudes were relatively elevated to alcohol cues, but only in individuals early in abstinence. Affective ratings of alcohol cues suggested that alcohol cues were perceived as aversive. Methodological and theoretical implications of the findings are discussed.
本研究调查了人类眨眼惊跳反射，以此作为酒精线索反应性的一种测量方法。处于戒酒早期（n = 36）和晚期（n = 34）的酒精依赖参与者观看了酒精和水的线索展示。与先前的研究一致，对酒精线索的反应是唾液分泌增加以及饮酒欲望评分升高。对酒精线索和水线索的唾液分泌及欲望反应差异并不会随着戒酒时长而变化。特别值得关注的是，惊跳反应幅度对酒精线索相对升高，但仅在戒酒早期的个体中出现。对酒精线索的情感评分表明，酒精线索被视为厌恶刺激。本文讨论了这些研究结果的方法学和理论意义。
