Rissanen A, Hakala P, Lissner L, Mattlar C-E, Koskenvuo M, Rönnemaa T
Department of Psychiatry, University of Helsinki, Finland.
Int J Obes Relat Metab Disord. 2002 Jul;26(7):973-7. doi: 10.1038/sj.ijo.0802014.
To determine the independent associations of dietary preference for fat with obesity without the confounding by genetic effects.
Descriptive comparison of the responses of monozygotic twins discordant for obesity to questions concerning current and past preference for dietary fat, current overconsumption of fatty items and recalled food consumption compared to the co-twin.
The Research and Development Centre of the Social Insurance Institution, Finland.
Twenty-three healthy monozygotic twin pairs who were discordant for obesity (BMI difference at least 3 kg/m(2)).
Obesity status of the twin, as a function of the current and recalled dietary preferences and selected psychosocial variables.
The obese twins reported current preference for fatty foods three times more frequently than the lean co-twin. Moreover, when comparing recalled taste for fat at the time the twins left their parental homes, both the obese and lean co-twins consistently recalled that the obese twin had greater preference for fatty foods in young adulthood, and that the lean twin had less. Psychological characteristics of lean and obese co-twins did not differ.
Acquired preference for fatty foods is associated with obesity, independent of genetic background. Modification of fat preferences may be an important step in the prevention of obesity in the general population.
确定脂肪饮食偏好与肥胖之间的独立关联，而不受基因效应的混杂影响。
对肥胖程度不一致的同卵双胞胎就当前和过去对膳食脂肪的偏好、当前对高脂肪食物的过度消费以及与双胞胎相比回忆起的食物消费情况等问题的回答进行描述性比较。
芬兰社会保险机构研发中心。
23对健康的同卵双胞胎，他们在肥胖程度上不一致（体重指数差异至少为3kg/m²）。
双胞胎的肥胖状况，作为当前和回忆起的饮食偏好以及选定的社会心理变量的函数。
肥胖的双胞胎报告当前对高脂肪食物的偏好频率是较瘦的双胞胎的三倍。此外，当比较双胞胎离开父母家时回忆起的对脂肪的口味时，肥胖和较瘦的双胞胎都一致回忆起肥胖的双胞胎在年轻时对高脂肪食物的偏好更强，而较瘦的双胞胎则较弱。较瘦和肥胖的双胞胎的心理特征没有差异。
对高脂肪食物的后天偏好与肥胖有关，与基因背景无关。改变对脂肪的偏好可能是普通人群预防肥胖的重要一步。
