Beuerlein I, Mariss P, Stangel W
Nucl Med (Stuttg). 1975 Aug 31;14(3):240-7.
The kinetic of 51Cr-labelled autologeous and heterologeous thrombocytes was studied in 12 healthy volunteers. The mean recovery value was 63% (SX = +/- 15%). The survival times (t50% and t10%) were determined as 94 hrs. (SX = +/- 11 hrs.) and as 202 hrs. (SX = +/- 13 hrs.) respectively. The "excess counts" over spleen and liver were measured and the spleen to liver ratio calculated. In every parameter investigated no significant difference between autologeous and heterologeous labelled thrombocytes could be found. The "excess counts" over spleen and liver were calculated on the basis of the radioactivity of blood and of the heart surface area. The values obtained from the blood radioactivity calculations showed significant lower variation coefficients than the corresponding values derived from the heart measurements.
在12名健康志愿者中研究了51Cr标记的自体和异体血小板的动力学。平均回收率为63%（标准误=±15%）。存活时间（t50%和t10%）分别确定为94小时（标准误=±11小时）和202小时（标准误=±13小时）。测量了脾脏和肝脏的“过量计数”并计算了脾肝比值。在所研究的每个参数中，未发现自体和异体标记血小板之间有显著差异。脾脏和肝脏的“过量计数”是根据血液放射性和心脏表面积计算得出的。从血液放射性计算得到的值显示出比从心脏测量得到的相应值显著更低的变异系数。
