Ott Z
Polim Med. 1975;5(2):167-73.
The author describes three variants of the surface treatment of PMMA using a special method suggested by Wichterle. Modified surfaces of PMMA discs in three variations A, B, C were followed in subcutaneous implantation in rats during three months and were well tolerated. The final stage was characterized by a stabilized fibrous capsule. The relationship between modified PMMA, glass and pure PMMA in vitro using human and animal blood was also investigated. The author analyzes experiments carried out with human blood (Lee-White's time of blood clotting and fibrin formation after Bürker) and proves better antithrombogenic properties of modified PMMA to control on glass and pure PMMA.
作者描述了使用维特彻莱提出的一种特殊方法对聚甲基丙烯酸甲酯（PMMA）进行表面处理的三种变体。对三种变体A、B、C的PMMA圆盘改性表面在大鼠皮下植入三个月期间进行了跟踪观察，发现它们耐受性良好。最后阶段的特征是形成了稳定的纤维囊。还研究了改性PMMA、玻璃和纯PMMA在体外与人血和动物血的关系。作者分析了用人血进行的实验（伯克法测定的Lee-White凝血时间和纤维蛋白形成时间），并证明改性PMMA比玻璃和纯PMMA具有更好的抗血栓形成性能。
