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鳞状牙源性肿瘤:诊断与治疗

Squamous odontogenic tumor: diagnosis and management.

作者信息

Haghighat Kamran, Kalmar John R, Mariotti Angelo J

机构信息

Section of Periodontology, College of Dentistry, The Ohio State University, Columbus 43218-2357, USA.

出版信息

J Periodontol. 2002 Jun;73(6):653-6. doi: 10.1902/jop.2002.73.6.653.

Abstract

The squamous odontogenic tumor (SOT) is a rare, benign, locally infiltrative neoplasm of the jaws that appears to originate from the rests of Malassez. It has been confused with other pathologic entities such as ameloblastomas, carcinomas, and fibromas and clinically may resemble localized periodontal disease. The tumor is often asymptomatic, although it can present with symptoms of pain and tooth mobility. A characteristic radiographic appearance is that of a triangular-shaped or semi-circular lucency associated with the roots of erupted teeth. Histologically, the tumor is characterized by the formation of variably sized nests and cords of uniform, benign-appearing, squamous epithelium with occasional vacuolization and keratinization. Treatment of SOT by conservative surgical excision is normally curative with rare episodes of recurrence reported. Since the clinical presentation of SOT may mimic more common pathologic entities, this case report reinforces the need for careful histologic evaluation of all lesions found in the periodontium.

摘要

鳞状牙源性肿瘤(SOT)是一种罕见的、良性的、具有局部浸润性的颌骨肿瘤,似乎起源于马拉瑟上皮剩余。它曾与其他病理实体如成釉细胞瘤、癌和纤维瘤相混淆,临床上可能类似局限性牙周病。该肿瘤通常无症状,不过也可能出现疼痛和牙齿松动的症状。其特征性的影像学表现是与萌出牙齿的牙根相关的三角形或半圆形透亮区。组织学上,该肿瘤的特征是形成大小不一的巢状和条索状结构,由形态一致、外观良性的鳞状上皮组成,偶尔有细胞空泡化和角化。通过保守性手术切除治疗SOT通常可治愈,报道的复发情况罕见。由于SOT的临床表现可能与更常见的病理实体相似,本病例报告强调了对牙周组织中发现的所有病变进行仔细组织学评估的必要性。

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