Meng M V, Carroll P R
Department of Urology, U-575, University of California, San Francisco, San Francisco, CA 94143-0738, USA.
Curr Urol Rep. 2001 Jun;2(3):237-41. doi: 10.1007/s11934-001-0085-x.
The necessity of pelvic lymph node dissection has been questioned in recent years as a result of improved pre-treatment staging based on clinical and pathologic factors. Accurate evaluation of nodal status allows rational selection of therapy and improved outcomes. Nevertheless, lymph node dissection may play a role even in patients with low stage disease (clinical T1c) despite an overall low risk for metastases. Herein we discuss recent advances in the evaluation of lymph nodes in stage T1c prostate cancer with respect to accurate prediction, radiologic imaging, molecular characterization, and operative considerations.
近年来，由于基于临床和病理因素的治疗前分期得到改善，盆腔淋巴结清扫术的必要性受到了质疑。准确评估淋巴结状态有助于合理选择治疗方法并改善治疗效果。然而，即使对于低分期疾病（临床T1c）的患者，尽管转移风险总体较低，但淋巴结清扫术仍可能发挥作用。在此，我们讨论T1c期前列腺癌淋巴结评估在准确预测、放射影像学、分子特征以及手术考量方面的最新进展。
