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鼻内镜检查与慢性鼻-鼻窦炎的定义及诊断

Nasal endoscopy and the definition and diagnosis of chronic rhinosinusitis.

作者信息

Stankiewicz James A, Chow James M

机构信息

Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, Maywood, IL, USA.

出版信息

Otolaryngol Head Neck Surg. 2002 Jun;126(6):623-7. doi: 10.1067/mhn.2002.125602.

Abstract

OBJECTIVES

Although endoscopy has been shown by a few authors to be a valuable tool for the diagnosis of chronic rhinosinusitis, its true role in the evaluation of the patient with chronic rhinosinusitis has not been elucidated. The current definition of chronic rhinosinusitis is a symptom-based definition, and objective testing such as endoscopy or computed tomography (CT) is not included. However, the current treatment paradigm for chronic rhinosinusitis is dependent on the definition for diagnosis. Patients are treated with 4 weeks of antibiotics and decongestant/antihistamines/steroids based on the definition. This study aims to evaluate in a prospective fashion the place of endoscopy in the diagnosis of chronic rhinosinusitis.

STUDY DESIGN

A group of 78 patients meeting the definition of chronic rhinosinusitis were subjected to same-day endoscopy and CT scanning.

RESULTS

Seventeen (22%) of 78 patients had positive endoscopic and CT results. There were 20 (26%) of 78 patients with negative endoscopic and positive CT results. Six (8%) patients had positive endoscopic and negative CT results, and 35 (45%) had negative endoscopic and negative CT results. Overall, 37 (47%) patients had positive CT results, and 41 (53%) patients had negative CT results. Endoscopy showing the presence of purulence, nasal polyps, or watery congested mucosa correlated well with CT results. Negative endoscopy correlated with CT results in 65% of patients.

CONCLUSION

The use of endoscopy to corroborate the diagnosis in nonpolypoid or nonpurulent rhinosinusitis in previously unoperated patients is questioned. Patients who meet the subjective definition of chronic rhinosinusitis should have a high degree of sensitivity and specificity with endoscopy or CT. The fact this is not the case questions the accuracy of the definition and the treatment paradigm.

SIGNIFICANCE

According to this study, positive endoscopic results correlated well with CT, and negative endoscopic results correlated in 71% of patients with negative CT results.

摘要

目的

尽管一些作者已表明内镜检查是诊断慢性鼻-鼻窦炎的一项重要工具,但其在慢性鼻-鼻窦炎患者评估中的真正作用尚未阐明。慢性鼻-鼻窦炎的当前定义是基于症状的定义,未纳入诸如内镜检查或计算机断层扫描(CT)等客观检测。然而,慢性鼻-鼻窦炎的当前治疗模式依赖于诊断定义。根据该定义,患者接受为期4周的抗生素及减充血剂/抗组胺药/类固醇治疗。本研究旨在以前瞻性方式评估内镜检查在慢性鼻-鼻窦炎诊断中的地位。

研究设计

一组78例符合慢性鼻-鼻窦炎定义的患者接受了当日内镜检查和CT扫描。

结果

78例患者中,17例(22%)内镜检查和CT结果均为阳性。78例患者中有20例(26%)内镜检查结果为阴性而CT结果为阳性。6例(8%)患者内镜检查结果为阳性而CT结果为阴性,35例(45%)患者内镜检查和CT结果均为阴性。总体而言,37例(47%)患者CT结果为阳性,41例(53%)患者CT结果为阴性。内镜检查显示存在脓性分泌物、鼻息肉或水样充血黏膜与CT结果相关性良好。65%的患者内镜检查结果阴性与CT结果相关。

结论

对于既往未接受手术的非息肉样或非脓性鼻-鼻窦炎患者,使用内镜检查来证实诊断受到质疑。符合慢性鼻-鼻窦炎主观定义的患者在内镜检查或CT检查中应具有高度的敏感性和特异性。但实际情况并非如此,这对定义的准确性和治疗模式提出了质疑。

意义

根据本研究,内镜检查结果阳性与CT结果相关性良好,71%的内镜检查结果阴性患者CT结果也为阴性。

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