Zinkernagel Rolf M
Institute for Experimental Immunology, University Hospital, Zurich, Switzerland.
Curr Opin Immunol. 2002 Aug;14(4):523-36. doi: 10.1016/s0952-7915(02)00367-9.
The evolutionary benefits of immunological memory are important: whereas antibodies can be transmitted to offspring by their mother and thereby benefit the species, T cell memory may function to help the individual combat persistent infection in peripheral tissues. Although experimental immunological memory is largely maintained antigen-independently, protective immunity is antigen-dependent.
抗体可由母亲传递给后代,从而使物种受益,而T细胞记忆可能有助于个体抵抗外周组织中的持续性感染。尽管实验性免疫记忆在很大程度上是不依赖抗原维持的,但保护性免疫是依赖抗原的。