Lentz Marianne, Nielsen Jørgen Feldbaek
Department of Neurology, Aarhus University Hospital, Denmark.
Clin Neurophysiol. 2002 Jul;113(7):1092-8. doi: 10.1016/s1388-2457(02)00031-7.
To characterize so-called central fatigue, the effect of various levels of exercise on central and peripheral motor potentials were compared.
Thirteen healthy subjects performed 4 levels of exercise following isometric dorsiflexion of the foot. Post-exercise recordings from the anterior tibial muscle of motor evoked potentials (MEP) evoked by transcranial magnetic stimulation (TMS) and M wave evoked by electrical stimulation of the peroneal nerve were performed.
After 5 s the post-exercise MEP amplitude increased. The increase was related to the degree of work performed. Subsequently, there was a gradually decrease of amplitude reaching statistical significance after 15 min. The area of the M wave increased significantly after 10 s and returned to baseline after 2-3 min.
Facilitation and depression of MEP after fatiguing exercise is at least partly a peripheral phenomenon dependent on the level of exercise performed.
为了描述所谓的中枢性疲劳，比较不同运动水平对中枢和外周运动电位的影响。
13名健康受试者在足部等长背屈后进行4个运动水平的运动。运动后记录经颅磁刺激（TMS）诱发的运动诱发电位（MEP）以及腓总神经电刺激诱发的M波，记录部位为胫前肌。
运动后5秒，MEP波幅增加。这种增加与运动强度有关。随后，波幅逐渐下降，15分钟后达到统计学意义。M波面积在10秒后显著增加，并在2 - 3分钟后恢复到基线水平。
疲劳运动后MEP的易化和抑制至少部分是一种外周现象，取决于运动水平。
