Coard K C M
Department of Pathology, University of the West Indies, Kingston 7, Jamaica.
West Indian Med J. 2002 Mar;51(1):40-3.
A prospective study of the clinico-pathological features of prostate cancer at the time of needle biopsy diagnosis was conducted in the Department of Pathology at the University Hospital of the West Indies over a one-year period. Ninety cases were diagnosed during this time. The mean age of patients at diagnosis was 72 years and the mean Gleason score of the biopsy, 7.3. Serum prostate-specific antigen levels were markedly elevated in the majority of patients, with a mean value of at least 159.8 ng/ml in the 76 patients for whom this information was available. The significance of these findings and that of other histopathological features examined are discussed, particularly in relation to recognized prognostic factors. It is concluded that the diagnosis of prostate cancer in Jamaica appears to be considerably later than that seen elsewhere. This information should provide support for those who advocate the introduction of a vigorous screening process for prostate cancer in Jamaica.
在西印度群岛大学医院病理科，对针吸活检诊断时前列腺癌的临床病理特征进行了为期一年的前瞻性研究。在此期间共诊断出90例病例。诊断时患者的平均年龄为72岁，活检的平均Gleason评分为7.3。大多数患者的血清前列腺特异性抗原水平显著升高，在有该信息的76例患者中，平均值至少为159.8 ng/ml。讨论了这些发现以及所检查的其他组织病理学特征的意义，特别是与公认的预后因素相关的意义。得出的结论是，牙买加前列腺癌的诊断似乎比其他地方晚得多。该信息应为那些主张在牙买加引入积极的前列腺癌筛查程序的人提供支持。
