Okumoto Tatsuo, Tomiyama Koji, Ino Hideo, Kanaya Yoshiaki, Maruyama Shuichiro, Otani Jun, Yokoyama Nobuji, Soda Mitsuhiro
Dept. of Surgery, Himeji St. Mary's Hospital.
Gan To Kagaku Ryoho. 2002 Jun;29(6):943-7.
We have encountered a case of malignant lymphoma of the stomach in which a complete remission was confirmed in a resected specimen after chemotherapy. A 75-year-old woman complained of vomiting blood. A biopsy from gastric endoscopy indicated malignant lymphoma of diffuse large B-cell type. The patient was assumed to be inoperable due to enlargement of the tumor and lymph node metastasis, and THP-COP chemotherapy was carried out. After four courses of the THP-COP regimen, endoscopic examination revealed a significant tumor reduction. Total gastrectomy and splenectomy with lymph node dissection (D2) were performed after chemotherapy. No tumor cells were detected in any sections of the specimen or regional lymph nodes.
我们遇到了一例胃恶性淋巴瘤患者，化疗后在切除标本中证实完全缓解。一名75岁女性主诉吐血。胃镜活检显示为弥漫性大B细胞型恶性淋巴瘤。由于肿瘤增大和淋巴结转移，该患者被认为无法手术，遂进行了THP - COP化疗。在进行四个疗程的THP - COP方案化疗后，内镜检查显示肿瘤明显缩小。化疗后进行了全胃切除术、脾切除术及淋巴结清扫（D2）。标本的任何切片或区域淋巴结中均未检测到肿瘤细胞。
