Tanizawa Yutaka, Terashima Masanori, Tokunaga Masanori, Bando Etsuro, Kawamura Taiichi, Kondo Junya, Waragai Mitsuru, Motegi Yoko, Sugisawa Norihiko, Ohshima Noriko, Taki Yusuke, Makuuchi Rie, Miki Yuichiro, Yamakawa Yushi, Kinugasa Yusuke, Kanemoto Hideyuki, Uesaka Katsuhiko, Onozawa Yusuke
Division of Gastric Surgery, Shizuoka Cancer Center.
Gan To Kagaku Ryoho. 2010 Nov;37(11):2155-60.
We reported a case of peritoneal disseminated recurrence after total gastrectomy for perforated gastric malignant lymphoma. A 73-year-old man underwent total gastrectomy for perforated gastric diffuse large B cell lymphoma on day 5 of RCHOP (rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone) chemotherapy. He has rejected chemotherapy and received no additional treatment after gastrectomy. Computer tomography 13 months after surgery revealed peritoneal dissemination and abdominal lymph node metastasis. R-CHOP chemotherapy was performed, and after 4 courses of chemotherapy, peritoneal dissemination and metastatic abdominal lymph nodes disappeared. Chemotherapy was discontinued for a time, however, the tumors relapsed 2 months after stopping chemotherapy. He underwent chemotherapy with etoposide, but died of tumor progression 21 months after gastrectomy.
我们报告了一例胃恶性淋巴瘤穿孔行全胃切除术后腹膜播散复发的病例。一名73岁男性在RCHOP（利妥昔单抗、环磷酰胺、羟基柔红霉素、长春新碱和泼尼松龙）化疗第5天因胃弥漫性大B细胞淋巴瘤穿孔接受了全胃切除术。他拒绝化疗，胃切除术后未接受其他治疗。术后13个月的计算机断层扫描显示腹膜播散和腹部淋巴结转移。进行了R-CHOP化疗，4个疗程化疗后，腹膜播散和腹部转移淋巴结消失。化疗曾一度中断，然而，化疗停止2个月后肿瘤复发。他接受了依托泊苷化疗，但在胃切除术后21个月死于肿瘤进展。
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