Wolff H, Kunte C
Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität, München.
Ther Umsch. 2002 May;59(5):251-5. doi: 10.1024/0040-5930.59.5.251.
Facial hypertrichosis and hirsutism may cause severe cosmetic and psychologic problems. There are several therapeutic options, both on the cosmetic and medical level. Hirsutism with androgen-excess should be diagnosed and treated by gynecologists. Although frequently used, systemic antiandrogens have not yet proven their efficacy against unwanted hypertrichosis in clinical studies using modern and objective endpoints. Conventional methods of hair removal include plucking, waxing and chemical depilation by thiogycolates, as well as electrolysis and thermolysis. A new medical treatment of hypertrichosis is eflornithine cream. It inhibits the enzyme ornithine-decarboxylase which is essential for the rapidly dividing cells of the hair follicle. Permanent depilation by photothermolysis with lasers and pulsed flash-light systems is currently the most promising treatment.
面部多毛症和多毛可能会导致严重的美容和心理问题。在美容和医学层面都有多种治疗选择。雄激素过多所致的多毛症应由妇科医生进行诊断和治疗。虽然全身用抗雄激素药物经常被使用，但在采用现代客观终点指标的临床研究中，尚未证实其对不必要的多毛症有疗效。传统的脱毛方法包括拔毛、打蜡以及用硫代乙醇酸盐进行化学脱毛，还有电解脱毛和热分解脱毛。一种治疗多毛症的新药物是依氟鸟氨酸乳膏。它能抑制鸟氨酸脱羧酶，而该酶对于毛囊快速分裂的细胞至关重要。目前，使用激光和脉冲闪光灯系统进行光热解永久性脱毛是最有前景的治疗方法。
