Kakeda Shingo, Nakamura Katsumi, Kamada Koji, Watanabe Hideyuki, Nakata Hajime, Katsuragawa Shigehiko, Doi Kunio
Department of Radiology, University of Occupational and Environmental Health School of Medicine, Iseigaoka 1-1, Yahatanisi-ku, Kitakyushu-shi 807-8555, Japan.
Radiology. 2002 Jul;224(1):145-51. doi: 10.1148/radiol.2241010719.
To evaluate the effect of a temporal subtraction technique for digital chest radiography with regard to the accuracy of detection of lung nodules.
Twenty solitary lung nodules smaller than 30 mm in diameter, including 10 lung cancers and 10 benign nodules, were used. The nodules were grouped subjectively according to their subtlety. For non-nodular cases, 20 nodules without perceptible interval changes were selected. All chest radiographs were obtained by using a computed radiographic system, and temporal subtraction images were produced by using a program developed at the University of Chicago. The effect of the temporal subtraction image was evaluated by using an observer performance study, with use of receiver operating characteristic analysis.
Observer performance with temporal subtraction images was substantially improved (A(z) = 0.980 and 0.958), as compared with that without temporal subtraction images (A(z) = 0.920 and 0.825) for the certified radiologists and radiology residents, respectively. The temporal subtraction technique clearly improved diagnostic accuracy for detecting lung nodules, especially subtle cases.
The temporal subtraction technique is useful for improving detection accuracy for peripheral lung nodules on digital chest radiographs.
评估数字胸部X线摄影的时间减影技术对肺结节检测准确性的影响。
使用20个直径小于30mm的孤立性肺结节，其中包括10个肺癌结节和10个良性结节。根据结节的细微程度进行主观分组。对于非结节病例，选择20个无明显间隔变化的结节。所有胸部X线片均使用计算机X线摄影系统获取，并使用芝加哥大学开发的程序生成时间减影图像。通过观察者性能研究，利用受试者操作特征分析来评估时间减影图像的效果。
与未使用时间减影图像相比，认证放射科医生和放射科住院医师使用时间减影图像时的观察者性能显著提高（认证放射科医生的A(z)值分别为0.980和0.958，放射科住院医师的A(z)值分别为0.920和0.825）。时间减影技术明显提高了检测肺结节的诊断准确性，尤其是细微病例。
时间减影技术有助于提高数字胸部X线片上周围型肺结节的检测准确性。
