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老年男性的常见病症:勃起功能障碍、良性前列腺增生、心血管疾病和抑郁症。

Common conditions of the aging male: erectile dysfunction, benign prostatic hyperplasia, cardiovascular disease and depression.

作者信息

Zakaria L, Anastasiadis A G, Shabsigh R

机构信息

Department of Urology, The College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.

出版信息

Int Urol Nephrol. 2001;33(2):283-92. doi: 10.1023/a:1015292603884.

Abstract

With increasing life expectancy, medical profession will be faced with the task of ensuring that the large, aging population remains healthy and vital despite the face of increasing healthcare costs. Naturally, urology as a specialty is concerned with important geriatric issues. This article will focus specifically on the aging male population and the health problems that most frequently plague them. Four major, non-cancer, disease states have been identified that adversely effect males over the age of 50. These conditions are: erectile dysfunction (ED), benign prostatic hyperplasia (BPH), cardiovascular disease (CVD) and depression. A literature search of PubMed was conducted using the key words ED, BPH, CVD and depression as well as ADAM (Androgen Decline in the Aging Male) and quality of life (QoL). NIH and WHO conference proceedings and publications were also referenced to insure detail and accuracy of data. Information was then organized and correlated in order to provide a detailed description of the key conditions and their interrelatedness. The spectrum of research performed thus far regarding this topic has done little to investigate the effects, causes and correlations between these conditions. Research has been done linking two or three of these conditions; however, there remains to be information discussing the four disease states in terms of their possible cause and effect relationships or the effectiveness of parallel, multi-disciplinary approach to their therapy. This report calls attention to the benefits of viewing and researching the above mentioned conditions as possibly interrelated, as opposed to the traditional view of them as separate, unrelated and independently treatable disease states. ED, BPH, CVD and depression are all common conditions that accompany aging and negatively impact QoL. They almost always develop with age and precipitate considerable morbidity and may even result in mortality. Furthermore, the presentation of one condition may correlate with the development of another. The inter-relation of these conditions, as evident from their underlying similarities, cause-and-effects relationships and therapeutic consequences, should be enough to warrant a multidisciplinary approach to their research. This approach, combined with careful choice of therapy, parallel and singular, will help providers reach their goal to keep patients healthy, and more importantly happy, late into their life, thus realizing the concept of "successful aging".

摘要

随着预期寿命的增加,医疗行业将面临一项任务,即确保庞大的老年人口尽管面临不断增加的医疗成本,但仍保持健康和活力。自然而然地,泌尿外科作为一个专科领域关注着重要的老年医学问题。本文将特别聚焦于老年男性群体以及最常困扰他们的健康问题。已确定有四种主要的非癌症疾病状态对50岁以上男性产生不利影响。这些病症分别是:勃起功能障碍(ED)、良性前列腺增生(BPH)、心血管疾病(CVD)和抑郁症。使用关键词ED、BPH、CVD、抑郁症以及“老年男性雄激素缺乏症(ADAM)”和生活质量(QoL)在PubMed上进行了文献检索。还参考了美国国立卫生研究院(NIH)和世界卫生组织(WHO)的会议记录及出版物,以确保数据的详细性和准确性。然后对信息进行整理和关联,以便详细描述关键病症及其相互关系。迄今为止,关于这个主题的研究范围几乎没有对这些病症之间的影响、成因和相关性进行调查。已经有研究将其中两三种病症联系起来;然而,仍有待有信息来讨论这四种疾病状态之间可能的因果关系,或者针对它们的平行多学科治疗方法的有效性。本报告提请注意将上述病症视为可能相互关联的益处,这与传统观点中将它们视为单独、不相关且可独立治疗的疾病状态形成对比。ED、BPH、CVD和抑郁症都是伴随衰老出现的常见病症,会对生活质量产生负面影响。它们几乎总是随着年龄增长而出现,引发相当高的发病率,甚至可能导致死亡。此外,一种病症的出现可能与另一种病症的发展相关。从这些病症潜在的相似性、因果关系和治疗后果来看,它们之间的相互关系应该足以保证对其进行多学科研究。这种方法,再结合对平行和单一治疗方法的谨慎选择,将有助于医疗服务提供者实现让患者在晚年保持健康,更重要的是保持快乐的目标,从而实现“成功老龄化”的理念。

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