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鸡提取物对易卒中型自发性高血压大鼠高血压发展的预防作用。

Preventive effect of a chicken extract on the development of hypertension in stroke-prone spontaneously hypertensive rats.

作者信息

Matsumura Yasuo, Kita Satomi, Ono Hiroyuki, Kiso Yoshinobu, Tanaka Takaharu

机构信息

Department of Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan.

出版信息

Biosci Biotechnol Biochem. 2002 May;66(5):1108-10. doi: 10.1271/bbb.66.1108.

DOI:10.1271/bbb.66.1108
PMID:12092823
Abstract

The antihypertensive effect of Brand's Essence of Chicken (BEC), a popular chicken extract used as a traditional health food, was examined with stroke-prone spontaneously hypertensive rats (SHRSPs). The animals were maintained from 6 to 25 weeks of age on drinking water with or without BEC. The BEC-fed group showed a significant reduction in the development of hypertension when compared with the control animals. The levels of blood urea nitrogen and plasma creatinine in the BEC-fed group were significantly lower than those in the control group, suggesting that the renal glomerular function had been improved by the daily administration of BEC. It thus seems likely that BEC would be useful as a prophylactic treatment against the development of hypertension and renal injury.

摘要

作为一种广受欢迎的鸡肉提取物并用作传统保健食品的Brand's鸡精(BEC),其对易患中风的自发性高血压大鼠(SHRSPs)的降压作用进行了研究。这些动物在6至25周龄期间饮用含或不含BEC的水。与对照动物相比,喂食BEC的组在高血压发展方面有显著降低。喂食BEC组的血尿素氮和血浆肌酐水平显著低于对照组,这表明每日给予BEC可改善肾小球功能。因此,BEC似乎可用作预防高血压和肾损伤发展的治疗方法。

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