Lachat M L, Pfammatter Th, Witzke H J, Bettex D, Künzli A, Wolfensberger U, Turina M I
Clinic for Cardiovascular Surgery, Zurich University Hospital, Switzerland.
Eur J Vasc Endovasc Surg. 2002 Jun;23(6):528-36. doi: 10.1053/ejvs.2002.1622.
acute haemodynamic changes and/or loss of abdominal muscle tone can occur during induction of general anaesthesia and may be the Achilles' tendon in endovascular aneurysm repair (EVAR) of ruptured aortoiliac aneurysms (rAIA). The purpose of this study was to evaluate the use of local anaesthesia (LA) for EVAR to overcome these limitations.
twenty-one consecutive patients with rAIA are included in this study. Twenty patients underwent EVAR under LA, and 1 patient was treated under general anaesthesia. Haemodynamics were stabilised during assessment of EVAR feasibility by CT-scan and during the procedure itself by controlled hypotension (MAP 50-60 mmHg) and moderate fluid resuscitation.
median procedure time was 120 min. Haemodynamics remained stable in all but 3 patients who required transfemoral balloon occlusion of the supra-renal aorta. Perioperative intubation was necessary in 5 patients because of respiratory distress (n=3), or retroperitoneal access (n=2). Temporary deterioration of renal function occurred in 6 patients, with 2 requiring hemofiltration. CT-scan confirmed sealing of the rAIA in all patients at discharge. 30-day mortality was 9.5% (2 deaths). In the median follow-up of 19 months, there were no deaths, but 3 endovascularre-interventions, 1 crossover femoro-femoral bypass, and 1 open surgical graft repair.
our series is the first to show that EVAR for rAIA can be safely performed under LA. This approach allows implantation of commercially available bifurcated SG and improves patient outcome.
在全身麻醉诱导期间可能会发生急性血流动力学变化和/或腹肌张力丧失,这可能是破裂性主髂动脉瘤(rAIA)血管内动脉瘤修复术(EVAR)的致命弱点。本研究的目的是评估使用局部麻醉(LA)进行EVAR以克服这些局限性。
本研究纳入了21例连续的rAIA患者。20例患者在局部麻醉下接受了EVAR,1例患者在全身麻醉下接受治疗。在通过CT扫描评估EVAR可行性期间以及在手术过程中通过控制性低血压(平均动脉压50 - 60 mmHg)和适度液体复苏来稳定血流动力学。
手术中位时间为120分钟。除3例需要经股动脉球囊阻断肾上主动脉的患者外,所有患者的血流动力学均保持稳定。5例患者因呼吸窘迫(n = 3)或腹膜后入路(n = 2)需要围手术期插管。6例患者出现肾功能暂时恶化,其中2例需要血液滤过。CT扫描证实所有患者出院时rAIA均已封闭。30天死亡率为9.5%(2例死亡)。在中位随访19个月时,无死亡病例,但有3次血管内再次干预、1次交叉股-股旁路手术和1次开放手术移植物修复。
我们的系列研究首次表明,rAIA的EVAR可以在局部麻醉下安全进行。这种方法允许植入市售的分叉型移植物,并改善患者预后。