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[膀胱癌患者根治性膀胱切除术后的并发症]

[Complications after radical cystectomy in patients with bladder carcinoma].

作者信息

Segura Martín Miguel, Salinas Sánchez Antonio, Lorenzo Romero Juan, Hernández Millán Ibrahim, Giménez Bachs José Miguel, Virseda Rodríguez Julio

机构信息

Servicio de Urología, Complejo Hospitalario y Universitario de Albacete, Albacete, España.

出版信息

Arch Esp Urol. 2002 May;55(4):383-93.

Abstract

OBJECTIVE

To describe the frequency and type of complications after radical cystectomy for cancer of the urinary bladder and their relationship with the different types of urinary diversion techniques utilized.

METHODS

We conducted a retrospective study of 166 patients who underwent radical cystectomy in the same department of urology over a period of 12 years. The intraoperative, early, late complications and the need for postoperative treatments are analyzed according to percentages, main trends, scatter and confidence interval.

RESULTS

87.3% of the patients were male. The most common tumor stage was pT3 (37.9%). Transintestinal urinary diversion was performed in 81.1%; the most common being cutaneous ureteroileostomy (44%) and external diversion (64.1%). 16.7% presented hyperchloremic metabolic acidosis. Intraoperative, early and late complications were observed in 53.6%, 47.5% and 71.1% of the survivors for each time period, respectively. 28.3% of the patients required some type of medical treatment in the course of their disease and 30.7% required some type of surgical or percutaneous procedure. The most frequent complications were intraoperative bleeding (50%), respiratory complications early postoperatively (12.6%) and chronic urinary infection as late complication (30.7%).

CONCLUSIONS

The high percentage of complications in our series is basically due to the fact that all types of complications, whether directly related or not to the disease and surgical procedure, were included. There was a higher incidence of late complications, the survival time being an important factor that influences the presentation of these complications. Complications are directly related to the type of urinary diversion performed, patient age, tumor stage and previous morbidity. The appearance of complications carries a high percentage of long-term complementary medical treatments or surgical and percutaneous procedures.

摘要

目的

描述膀胱癌根治性膀胱切除术后并发症的发生率、类型及其与所采用的不同尿流改道技术的关系。

方法

我们对166例在同一泌尿外科接受了为期12年的根治性膀胱切除术的患者进行了回顾性研究。根据百分比、主要趋势、散点图和置信区间分析术中、早期、晚期并发症以及术后治疗需求。

结果

87.3%的患者为男性。最常见的肿瘤分期为pT3(37.9%)。81.1%的患者采用了经肠道尿流改道;最常见的是皮肤输尿管回肠造口术(44%)和外置引流(64.1%)。16.7%的患者出现高氯性代谢性酸中毒。在每个时间段,分别有53.6%、47.5%和71.1%的幸存者出现术中、早期和晚期并发症。28.3%的患者在病程中需要某种类型的药物治疗,30.7%的患者需要某种类型的手术或经皮手术。最常见的并发症是术中出血(50%)、术后早期呼吸并发症(12.6%)和晚期慢性尿路感染(30.7%)。

结论

我们系列研究中并发症的高发生率主要是由于纳入了所有类型的并发症,无论其是否与疾病和手术直接相关。晚期并发症的发生率较高,生存时间是影响这些并发症出现的一个重要因素。并发症与所进行的尿流改道类型、患者年龄、肿瘤分期和既往发病率直接相关。并发症的出现意味着有很大比例的患者需要长期的辅助药物治疗或手术及经皮手术。

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