Asano Kenichiro, Ohkuma Hiroki, Kudo Kanae, Takemura Atuhito, Suzuki Shigeharu, Kubo Osami
Department of Neurosurgery, Hirosaki University, School of Medicine, Zaifu-cho 5, Hirosaki, Aomori 036-8562, Japan.
No Shinkei Geka. 2002 Jun;30(6):631-7.
We report successful operations for a meningeal hemangiopericytoma using sufficient amounts of Preoperative Autologous Transfusion (PAT) and Hemodilutional Autologous Transfusion (HAT). A 23-year-old woman with amenorrhea and bilateral visual field disturbance was found to have a huge intracranial tumor. MRI showed a well-enhanced cystic mass in the left middle fossa, suprasellar, intrasellar, sphenoidal sinus, and cavernous sinus. Preoperatively, the tumor was thought to be a cystic pituitary tumor or meningioma. Surgical removal was planned in three steps. The first operation was carried out via the transsphenoidal approach. Total blood loss was 1348 ml and 2 MAP infusion were required to control bleeding. Histopathological diagnosis was hemangiopericytoma. After preparation of PAT 400 ml and HAT 800 ml, we carried out the second partial removal operation mainly via the interhemispheric approach. Total blood loss was 1829 ml and required autologous transfusion only. After preparation of PAT 1200 ml and HAT 400 ml, the last total removal operation was carried out mainly via the pterional and subtemporal approach. Total blood loss was 1813 ml and required autologous transfusion only. We needed 2 MAP infusion in the first operation, but were able to perform total removal successfully without homologous blood transfusion because a sufficient amount of PAT and HAT had been prepared preoperatively. Hemangiopericytoma required postoperative radiation therapy to avoid local recurrence. After successful removal of the tumor surgically, postoperative radiation therapy was able to be carried out efficiently.
我们报告了使用足量术前自体输血(PAT)和血液稀释自体输血(HAT)成功治疗脑膜血管外皮细胞瘤的手术案例。一名23岁闭经且伴有双侧视野障碍的女性被发现患有巨大颅内肿瘤。磁共振成像(MRI)显示左侧中颅窝、鞍上、鞍内、蝶窦和海绵窦有一个强化良好的囊性肿块。术前,该肿瘤被认为是囊性垂体瘤或脑膜瘤。计划分三步进行手术切除。第一次手术通过经蝶窦入路进行。总失血量为1348毫升,控制出血需要输注2次平均动脉压(MAP)。组织病理学诊断为血管外皮细胞瘤。在准备了400毫升PAT和800毫升HAT后,我们主要通过半球间入路进行了第二次部分切除手术。总失血量为1829毫升,仅需自体输血。在准备了1200毫升PAT和400毫升HAT后,最后一次全切除手术主要通过翼点和颞下入路进行。总失血量为1813毫升,仅需自体输血。我们在第一次手术中需要输注2次MAP,但由于术前已准备了足量的PAT和HAT,因此能够在不进行异体输血的情况下成功进行全切除。血管外皮细胞瘤术后需要放疗以避免局部复发。在手术成功切除肿瘤后,术后放疗得以有效进行。