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关注阿立哌唑。 (注:原文中药物名称有误,正确的是阿立哌唑,而不是amisulpride,amisulpride是氨磺必利)

Focus on amisulpride.

作者信息

Green Ben

机构信息

University of Liverpool, UK.

出版信息

Curr Med Res Opin. 2002;18(3):113-7. doi: 10.1185/030079902125000363.

Abstract

Amisulpride is a second-generation antipsychotic, a substituted benzamide. It appears to be an effective agent in treating schizophrenia for what are characterised as positive and negative symptoms. The recommended doses are between 400 mg/day and 800 mg/day. Amisulpride demonstrates a good global safety profile, particularly when compared with first-generation antipsychotics, such as haloperidol. There are interesting studies that point towards amisulpride's antidepressant effect in dysthymia speculative on possible roles in affective psychoses and chronic fatigue syndrome.

摘要

氨磺必利是一种第二代抗精神病药物,属于取代苯甲酰胺类。它似乎是治疗精神分裂症阳性和阴性症状的有效药物。推荐剂量为每日400毫克至800毫克。氨磺必利具有良好的整体安全性,尤其是与第一代抗精神病药物如氟哌啶醇相比。有一些有趣的研究指出氨磺必利对心境恶劣有抗抑郁作用,推测其在情感性精神病和慢性疲劳综合征中可能发挥作用。

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