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肾上皮细胞脱屑作为人体汞排泄途径的初步研究

Desquamation of renal epithelial cells as a route of mercury excretion in man: a preliminary study.

作者信息

Suzuki T, Shishido S

出版信息

Tohoku J Exp Med. 1975 Dec;117(4):397-8. doi: 10.1620/tjem.117.397.

DOI:10.1620/tjem.117.397
PMID:1209617
Abstract

Urine of mercury-exposed workers in a chlorine manufacturing factory and of staffs of our laboratory was separated in the supernatant solution and the precipitate by a centrifugation of 105,000 Xg for 60 min. The ratio of the amount of inorganic mercury in the precipitate to that in the supernatant solution ranged from 0.23 to 4.84, and was dependent upon the level of urinary mercury. The role of the desquamation of tubular cells is suggested as a possible route of urinary excretion of mercury.

摘要

一家氯制造厂中接触汞的工人以及我们实验室工作人员的尿液,通过在105,000×g的条件下离心60分钟,分离为上清液和沉淀物。沉淀物中无机汞的量与上清液中无机汞的量之比在0.23至4.84之间,且取决于尿汞水平。提示肾小管细胞脱落可能是汞经尿液排泄的一条途径。

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