Nagakawa Hiroyasu, Mikami Makoto, Takahashi Yoshihiko, Yatomi Mari, Takenouchi Toshinao
Department of Internal Medicine, Chosei General Hospital, Honnou 2777, Mobara 299-4192, Japan.
Nihon Kokyuki Gakkai Zasshi. 2002 Apr;40(4):299-303.
The patient was a 61-year-old man whose chest radiography showed infiltration in both lung fields. MALT lymphoma was diagnosed from transbronchial lung biopsy (TBLB) specimens. The serum monoclonal IgM level then increased, and plasma cells and lymphoplasmacytoid cells were found in a bone marrow examination, indicating macroglobulinemia as a complication. Despite chemotherapy, systemic metastasis led to the patient's death. Our report is accompanied with a review of literature, because no report of MALT lymphoma of pulmonary origin complicated with macroglobulinemia exists, and it is considered that the macroglobulinemia in this case was related to the MALT lymphoma.