Tarasova L N, Grigor'eva E F, Abaimov M A, Andronova O A
Vestn Oftalmol. 2002 Mar-Apr;118(2):32-4.
Twenty patients with normal pressure glaucoma (NPD) were examined. Concomitant cardiovascular diseases were diagnosed in 19 (95%) of them. Echocardioscopy with color mapping showed various diseases with left-ventricular dysfunction in 8 examinees. Dopplerography of orbital vessels showed a significant decrease of bloodflow velocity in the orbital artery and increased peripheral resistance indexes in the orbital and central retinal arteries in 20 NPD patients in comparison with healthy controls (p < 0.05, p < 0.01). Atherosclerotic involvement of the internal carotid artery was detected in 15 of 20 patients, in 4 of these with hemodynamically significant sclerosis of more than 50%. The contribution of cardiovascular disease to decrease of orbital bloodflow is discussed.
对20例正常眼压性青光眼(NPD)患者进行了检查。其中19例(95%)被诊断患有心血管疾病。彩色映射超声心动图显示8名受检者存在各种伴有左心室功能障碍的疾病。与健康对照组相比,20例NPD患者的眼眶血管多普勒检查显示眼眶动脉血流速度显著降低,眼眶和视网膜中央动脉的外周阻力指数增加(p < 0.05,p < 0.01)。20例患者中有15例检测到颈内动脉粥样硬化累及,其中4例血流动力学显著硬化超过50%。文中讨论了心血管疾病对眼眶血流减少的影响。