Grigor'eva E G, Tarasova L N, Abaimov M A
Vestn Oftalmol. 2002 Jul-Aug;118(4):6-8.
Bloodflow in the orbital artery and central retinal artery was studied by triplex scanning in 35 patients with normal pressure glaucoma, and 14 subjects without signs of glaucoma. Significant differences in the studied parameters were detected in the patients in comparison with the controls: decreased linear bloodflow velocity in the orbital (p < 0.01) and central retinal arteries (p < 0.01), increased peripheral resistance indexes in both arteries (p < 0.05) in patients with normal pressure glaucoma, and decreased bloodflow velocity in the central retinal artery in primary open-angle glaucoma (p < 0.05). The time course of hemodynamic parameters was different in normal pressure and primary open-angle glaucoma. These data confirm the important role of vascular disorders in the pathogenesis of normal pressure glaucoma.
通过三重扫描研究了35例正常眼压性青光眼患者和14例无青光眼体征受试者的眶动脉和视网膜中央动脉血流情况。与对照组相比，在患者中检测到研究参数存在显著差异：正常眼压性青光眼患者的眶动脉（p < 0.01）和视网膜中央动脉（p < 0.01）线性血流速度降低，两条动脉的外周阻力指数均升高（p < 0.05），原发性开角型青光眼患者的视网膜中央动脉血流速度降低（p < 0.05）。正常眼压性青光眼和原发性开角型青光眼的血流动力学参数随时间变化的过程有所不同。这些数据证实了血管紊乱在正常眼压性青光眼发病机制中的重要作用。
