[Antiprotease activity of the inhibitor from dog submandibular salivary glands].

The influence of trielin, an inhibitor from dog submandibular salivary glands, was studied as applied to the activity of elastase, trypsin and chemotrypsin determined by their degrading action on protein and synthetic substrates. The inhibition constants were calculated for the enzymes. The inhibitory effect of trielin was especially developed on the trypsin when using N-alpha-benzoyl-arginine-p-nitroanilide as a substrate. On the basis of inhibition constants the affinity of different substrates to elastase trypsin and chemotrypsin was shown.