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[影响脊柱转移瘤预后的因素分析]

[Analysis of factors affecting the prognosis of vertebral metastases].

作者信息

Riegel T, Schilling T, Sitter H, Benes L, Wilke A, Gross M W, Bertalanffy H

机构信息

Klinik für Neurochirurgie Philipps Universität Marburg, Germany.

出版信息

Zentralbl Neurochir. 2002;63(1):2-6. doi: 10.1055/s-2002-31578.

Abstract

The goal of this study was to evaluate factors for the prognosis of patients with metastatic spinal tumors. 139 patients with vertebral metastases were studied. The modified Tokuhashi Score (a preoperative score composed of six parameters) and single factors were analysed with statistical methods. The modified Tokuhashi Score showed a significant correlation (p = 0,0019) with survival time of patients. Additionally, only the Karnofsky Index as single parameter showed statistically significant correlation(p = 0.0016). Regarding the logistic regression, primary tumor, age, sex and Karnofsky Index were identified as prognostic factors for survival time. This trial could demonstrate that the Tokuhashi Score is a successful predicting tool for the assessment of prognosis of patients with vertebral metastases.

摘要

本研究的目的是评估转移性脊柱肿瘤患者的预后因素。对139例椎体转移患者进行了研究。采用统计方法分析改良Tokuhashi评分(由六个参数组成的术前评分)和单因素。改良Tokuhashi评分与患者生存时间呈显著相关性(p = 0.0019)。此外,仅卡氏指数作为单一参数显示出统计学显著相关性(p = 0.0016)。关于逻辑回归分析,原发肿瘤、年龄、性别和卡氏指数被确定为生存时间的预后因素。该试验表明,Tokuhashi评分是评估椎体转移患者预后的一种成功的预测工具。

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