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[儿童胃炎相关性幽门螺杆菌感染的治疗]

[Treatment of gastritis-associated Helicobacter pylori infection in children].

作者信息

Velasco Benítez Carlos Alberto, Amorocho Pérez Rubén Darío

机构信息

Pediatra, Gastroenterólogo y Nutriólogo, Universidad Industrial de Santander, Columbia.

出版信息

Rev Gastroenterol Peru. 2002 Apr-Jun;22(2):159-63.

PMID:12098744
Abstract

Helicobacter pylori (Hp) the gram-negative bacteria succeeding in surviving in such an unreceptive medium as the gastric mucosa, has been associated with an important group of diseases in childhood with subsequent consequences in adulthood. Evidence has shown that Hp optimum treatment requires multi-drug regime due to its high ability to become resistant. This article presents the most recommended courses of therapy to treat Hp, as well as re-infection and resistance rates worldwide, analyzing the existing policies for Hp eradication and follow-up. Finally, we include our personal experience in prevalence and management of Hp found in endoscopies.

摘要

幽门螺杆菌(Hp)是一种革兰氏阴性菌,成功在胃黏膜这种不友好的环境中存活,它与儿童时期的一组重要疾病有关,在成年后会产生后续影响。有证据表明,由于幽门螺杆菌极易产生耐药性,其最佳治疗需要采用多药联合方案。本文介绍了治疗幽门螺杆菌最推荐的治疗方案,以及全球范围内的再感染率和耐药率,分析了现有的幽门螺杆菌根除及随访政策。最后,我们纳入了在内镜检查中发现的幽门螺杆菌流行情况及管理方面的个人经验。

相似文献

1
[Treatment of gastritis-associated Helicobacter pylori infection in children].[儿童胃炎相关性幽门螺杆菌感染的治疗]
Rev Gastroenterol Peru. 2002 Apr-Jun;22(2):159-63.
2
[Resolution of an autoimmune thrombocytopenic purpura after eradicating treatment of Helicobacter pylori].[幽门螺杆菌根除治疗后自身免疫性血小板减少性紫癜的缓解]
Sangre (Barc). 1999 Oct;44(5):387-8.
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[Treatment of peptic ulcer and gastritis associated with Helicobacter pylori].[幽门螺杆菌相关性消化性溃疡和胃炎的治疗]
Enferm Infecc Microbiol Clin. 1995 Aug-Sep;13(7):422-8.
4
The efficacy of two-week therapy with ranitidine bismuth citrate, amoxicillin and clarithromycin on Helicobacter pylori eradication in clarithromycinresistant and- sensitive cases.枸橼酸铋雷尼替丁、阿莫西林和克拉霉素两周疗法对克拉霉素敏感及耐药病例中幽门螺杆菌根除的疗效。
Turk J Gastroenterol. 2005 Dec;16(4):203-6.
5
Cure of Helicobacter pylori: a hidden curse?幽门螺杆菌的治愈:一种隐藏的祸根?
Am J Gastroenterol. 1997 Dec;92(12):2313-4.
6
[Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin].[雷尼替丁、碱式水杨酸铋和克拉霉素联合应用根除复发性腹痛患者的幽门螺杆菌]
Acta Gastroenterol Latinoam. 1996;26(5):281-3.
7
[Eradication of Helicobacter pylori infection in Europe: a meta-analysis based on congress abstracts, 1997-2002].[欧洲幽门螺杆菌感染的根除:基于1997 - 2002年会议摘要的荟萃分析]
Orv Hetil. 2004 Oct 3;145(40):2035-41.
8
Eradication therapy of Helicobacter pylori directly induces apoptosis in inflammation-related immunocytes in the gastric mucosa--possible mechanism for cure of peptic ulcer disease and MALT lymphoma with a low-grade malignancy.幽门螺杆菌根除治疗直接诱导胃黏膜中炎症相关免疫细胞凋亡——这可能是消化性溃疡疾病和低度恶性黏膜相关淋巴组织淋巴瘤治愈的机制。
Hepatogastroenterology. 2003 May-Jun;50(51):607-9.
9
Can lansoprazole, amoxicillin, and clarithromycin combination still be used as a first-line therapy for eradication of helicobacter pylori?兰索拉唑、阿莫西林和克拉霉素联合用药仍可作为根除幽门螺杆菌的一线治疗方案吗?
Turk J Gastroenterol. 2005 Mar;16(1):29-33.
10
Maintenance treatment is not necessary after Helicobacter pylori eradication and healing of bleeding peptic ulcer: a 5-year prospective, randomized, controlled study.幽门螺杆菌根除及出血性消化性溃疡愈合后无需维持治疗:一项5年前瞻性、随机、对照研究。
Arch Intern Med. 2003 Sep 22;163(17):2020-4. doi: 10.1001/archinte.163.17.2020.

引用本文的文献

1
PELA microspheres loaded H. pylori lysates and their mucosal immune response.载有幽门螺杆菌裂解物的聚乳酸-乙醇酸共聚物微球及其黏膜免疫反应。
World J Gastroenterol. 2002 Dec;8(6):1098-102. doi: 10.3748/wjg.v8.i6.1098.