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[儿童胃炎相关性幽门螺杆菌感染的治疗]

[Treatment of gastritis-associated Helicobacter pylori infection in children].

作者信息

Velasco Benítez Carlos Alberto, Amorocho Pérez Rubén Darío

机构信息

Pediatra, Gastroenterólogo y Nutriólogo, Universidad Industrial de Santander, Columbia.

出版信息

Rev Gastroenterol Peru. 2002 Apr-Jun;22(2):159-63.

Abstract

Helicobacter pylori (Hp) the gram-negative bacteria succeeding in surviving in such an unreceptive medium as the gastric mucosa, has been associated with an important group of diseases in childhood with subsequent consequences in adulthood. Evidence has shown that Hp optimum treatment requires multi-drug regime due to its high ability to become resistant. This article presents the most recommended courses of therapy to treat Hp, as well as re-infection and resistance rates worldwide, analyzing the existing policies for Hp eradication and follow-up. Finally, we include our personal experience in prevalence and management of Hp found in endoscopies.

摘要

幽门螺杆菌(Hp)是一种革兰氏阴性菌,成功在胃黏膜这种不友好的环境中存活,它与儿童时期的一组重要疾病有关,在成年后会产生后续影响。有证据表明,由于幽门螺杆菌极易产生耐药性,其最佳治疗需要采用多药联合方案。本文介绍了治疗幽门螺杆菌最推荐的治疗方案,以及全球范围内的再感染率和耐药率,分析了现有的幽门螺杆菌根除及随访政策。最后,我们纳入了在内镜检查中发现的幽门螺杆菌流行情况及管理方面的个人经验。

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