[雷尼替丁、碱式水杨酸铋和克拉霉素联合应用根除复发性腹痛患者的幽门螺杆菌]
[Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin].
作者信息
Ramirez Mayans J A, Zamora Davila E, Cervantes Bustamante R, Mata Rivera N, Oyervides Garcia I, Cuevas S, Zarate Mondragón F E
机构信息
Servicio de Gastroenterología y nutrición, Instituto Nacional de Pediatría, México, DF.
出版信息
Acta Gastroenterol Latinoam. 1996;26(5):281-3.
OBJECTIVE
Elimination of Helicobacter pylori with Chlaritromicin, Bismuth subsalicylate and Ranitidine; and improvement of recurrent abdominal pain. ANTECEDENT: Different antibiotics, antagonist H2 and others has been used for elimination and, or eradication of Helicobacter pylori.
METHOD
22 children with recurrent abdominal pain associated to gastritis and histologic identification of Helicobacter pylori were studied under a period of 18 months (january 1992 to june 1993), at Instituto Nacional de Pediatría, México, D:F: All children were treated simultaneously with: Chlaritromicin, 15 days, Plus ranitidine and bismuth subsalicylate for one month.
RESULTS
Helicobacter pylori was eliminate in 14 of 22 children studied. All these children had an important improvement of recurrent abdominal pain.
CONCLUSION
Elimination of Helicobacter pylori and clinical improvement was present in 14 of 22 children studied (63.7%).
目的
使用克拉霉素、次水杨酸铋和雷尼替丁根除幽门螺杆菌，并改善复发性腹痛。
背景
已使用不同的抗生素、H2拮抗剂及其他药物来消除和/或根除幽门螺杆菌。
方法
1992年1月至1993年6月期间，在墨西哥城国家儿科研究所对22名与胃炎相关的复发性腹痛且经组织学鉴定有幽门螺杆菌的儿童进行了为期18个月的研究。所有儿童同时接受治疗：克拉霉素，疗程15天，加雷尼替丁和次水杨酸铋，疗程1个月。
结果
在22名接受研究的儿童中，14名儿童的幽门螺杆菌被根除。所有这些儿童的复发性腹痛都有显著改善。
结论
在22名接受研究的儿童中，14名儿童（63.7%）实现了幽门螺杆菌的根除和临床改善。
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