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婴儿脂溢性皮炎和特应性皮炎是同一种疾病的临床变体吗?

Are infantile seborrheic and atopic dermatitis clinical variants of the same disease?

作者信息

Moises-Alfaro Celia B, Caceres-Rios Hector W, Rueda Monica, Velazquez-Acosta Alvaro, Ruiz-Maldonado Ramon

机构信息

Department of Dermatology, Institute for Child Health, Lima, Peru.

出版信息

Int J Dermatol. 2002 Jun;41(6):349-51. doi: 10.1046/j.1365-4362.2002.01497.x.

DOI:10.1046/j.1365-4362.2002.01497.x
PMID:12100690
Abstract

BACKGROUND

The relationship between infantile seborrheic dermatitis (ISD) and infantile atopic dermatitis (IAD) is controversial.

METHODS

Ninety-six children aged 2-12 months diagnosed with atopic dermatitis and a comparable control group of healthy children were evaluated. Demographic data, personal history of ISD and personal or family history of atopy was considered in both groups.

RESULTS

A personal history of ISD was found in 49% of IAD cases and in 17% of controls (P < 0.05).

CONCLUSIONS

Our result and those of the literature do not demonstrate a relationship between ISD and IAD. However, a number of cases of AD have an ISD-like clinical picture. It is probable that ISD is a syndrome and not a disease.

摘要

背景

婴儿脂溢性皮炎(ISD)与婴儿特应性皮炎(IAD)之间的关系存在争议。

方法

对96名年龄在2至12个月被诊断为特应性皮炎的儿童以及一组与之匹配的健康儿童对照组进行评估。两组均考虑人口统计学数据、ISD个人史以及特应性个人或家族史。

结果

49%的IAD病例有ISD个人史,而对照组为17%(P < 0.05)。

结论

我们的结果以及文献中的结果均未表明ISD与IAD之间存在关联。然而,许多特应性皮炎病例有类似ISD的临床表现。ISD很可能是一种综合征而非一种疾病。

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