Ruiz-Maldonado R, López-Matínez R, Pérez Chavarría E L, Rocio Castañón L, Tamayo L
Department of Dermatology, Instituto Nacional de Pediatría, México City.
Pediatr Dermatol. 1989 Mar;6(1):16-20. doi: 10.1111/j.1525-1470.1989.tb00260.x.
The presence of Pityrosporum ovale was investigated in four groups of infants age 1 to 24 months, 15 with infantile seborrheic dermatitis, 15 with infantile atopic dermatitis, 15 with other infantile dermatoses, and 15 healthy infants. Samples were taken from the scalp, face, presternal area, and inguinal area. Pityrosporum ovale was detected by smears and/or cultures in 73% of infants with seborrheic dermatitis, 33% with atopic dermatitis, 33% with other dermatoses, and 53% of healthy infants. The percentages of positive smears and/or cultures from four body sites in each patient group were 42% for seborrheic dermatitis, 20% for atopic dermatitis, 20% for other infantile dermatoses, and 23% for healthy infants. The majority of infants with positive cultures or positive direct examination for P. ovale were between 1 and 8 months of age. The organism was isolated in 28% of samples taken from the scalp, 32% from the face, 30% from the presternal area, and 15% from the inguinal area. Patients with infantile seborrheic dermatitis were treated with 2% topical ketoconazole cream for two weeks. Eleven of these children were clinically cleared and 13 became mycologically negative. Pityrosporum ovale was significantly more frequent in infants with seborrheic dermatitis than in those with atopic dermatitis, in other infantile dermatoses, or in healthy infants, both in the total number of infants with positive smears and/or cultures and in the number of positive samples per body area (P less than 0.05).
对四组1至24个月大的婴儿进行了卵形糠秕孢子菌检测，其中15例患有婴儿脂溢性皮炎，15例患有婴儿特应性皮炎，15例患有其他婴儿皮肤病，以及15例健康婴儿。样本取自头皮、面部、胸骨前区和腹股沟区。通过涂片和/或培养，在73%的脂溢性皮炎婴儿、33%的特应性皮炎婴儿、33%的其他皮肤病婴儿以及53%的健康婴儿中检测到卵形糠秕孢子菌。每组患者四个身体部位涂片和/或培养阳性的百分比分别为：脂溢性皮炎42%，特应性皮炎20%，其他婴儿皮肤病20%，健康婴儿23%。大多数培养阳性或直接检查卵形糠秕孢子菌阳性的婴儿年龄在1至8个月之间。该菌在28%的头皮样本、32%的面部样本、30%的胸骨前区样本和15%的腹股沟区样本中被分离出来。患有婴儿脂溢性皮炎的患者用2%的外用酮康唑乳膏治疗两周。其中11名儿童临床症状消失，13名真菌学检查转阴。无论是涂片和/或培养阳性的婴儿总数，还是每个身体部位阳性样本的数量，脂溢性皮炎婴儿中的卵形糠秕孢子菌都显著多于特应性皮炎婴儿、其他婴儿皮肤病婴儿或健康婴儿（P<0.05）。
