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[核黄素对因蛋白质和胆碱缺乏而发生的黄嘌呤尿的影响]

[Influence of riboflavin on xanthuria leveloping as a result of protein and choline deficiency].

作者信息

Smirnova M G, Ekimovskiĭ A P

出版信息

Vopr Pitan. 1975 Sep-Oct(5):46-9.

PMID:1210201
Abstract

In growing male-rats intensively excreting xanthuric acid under the effect of rations deficient in protein and choline the passage of riboflavin with urine was determined. A series of tests with deficient choline in conjunction with a well-marked protein shortage revealed an intensive passage of riboflavin. On the other hand, a series of tests with deficient choline against the background of a moderate protein shortage failed to show any difference in the passage of riboflavin by test and control anomals. A single administration of 200 gamma of riboflavin to rats helped bring down elevated concentrations of xanthuric acid in the urine.

摘要

在蛋白质和胆碱缺乏日粮作用下大量排泄黄尿酸的生长雄性大鼠中,测定了核黄素随尿液的排出情况。一系列胆碱缺乏并伴有明显蛋白质缺乏的试验显示核黄素大量排出。另一方面,一系列胆碱缺乏且蛋白质轻度缺乏的试验未显示试验组和对照组动物在核黄素排出方面有任何差异。给大鼠单次注射200微克核黄素有助于降低尿液中升高的黄尿酸浓度。

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