Volgarev M N, Smirnova M G, Ekimovskiĭ A P
Vopr Pitan. 1979 Mar-Apr(2):53-5.
The parallelism between xanthurenuria and liver affections caused by protein and choline deficiency was studied. At the stages marking the development of lipohepatosis and fibrosis there occurred an intensive passage of xanthurenic acid. The intensity of xanthurenuria at the stage marking the appearance of hyperplastic nodes continued to gain strength. With progressive advance of pathological changes, which by the 9--12th months of the experiment reached the stage of a fully developed nodular cirrhosis xanthurenuria gradually stopped.
研究了黄尿酸尿症与蛋白质和胆碱缺乏引起的肝脏病变之间的平行关系。在标志着脂肪肝和纤维化发展的阶段,黄尿酸有强烈的排出。在标志着增生性结节出现的阶段,黄尿酸尿症的强度持续增强。随着病理变化的进展,到实验的第9至12个月达到完全发展的结节性肝硬化阶段时,黄尿酸尿症逐渐停止。