Hu J, Li J, Wang D, Buckley M J, Agarwal S
Department of Oral and Maxillofacial Surgery, Huaxi School of Stomatology, Sichuan University, Chengdu, China.
Int J Oral Maxillofac Surg. 2002 Apr;31(2):185-9. doi: 10.1054/ijom.2001.0193.
Corticotomy or osteotomy was performed on opposing sides of the mandibles in 18 goats. A custom-made distractor was used to lengthen the mandible at a rate of 1 mm/day for 10 days (total 10 mm elongation). Six goats were sacrificed respectively at 2, 4 and 8 weeks after completion of distraction. The distracted calluses were harvested and processed for radiographic, histologic, and scanning electron microscopic evaluation as well as Ca/P ratio analysis. The regenerate bone in the corticotomy side showed more bone formation and earlier mineralization than in the osteotomy side. The results of this study suggest that preservation of intramedullary vessels is beneficial to bone regeneration following mandibular osteodistraction, and that performing corticotomy may be a simple but effective way to promote the maturity of the distracted callus and shorten the time for fixation.
对18只山羊的下颌骨相对两侧进行皮质切开术或截骨术。使用定制的牵张器以每天1毫米的速度延长下颌骨，持续10天（总共延长10毫米）。在牵张完成后的第2、4和8周分别处死6只山羊。采集牵张部位的骨痂并进行放射学、组织学、扫描电子显微镜评估以及钙/磷比值分析。皮质切开术侧的再生骨比截骨术侧显示出更多的骨形成和更早的矿化。本研究结果表明，保留髓内血管有利于下颌骨牵张成骨后的骨再生，并且进行皮质切开术可能是促进牵张骨痂成熟和缩短固定时间的一种简单而有效的方法。
