[感染流感病毒标准株和“缺陷”株病毒粒子的细胞中的病毒特异性合成（作者译）]

[Virus-specific syntheses in cells infected with the virions from standard and "defective" populations of the influenza virus (author's transl)].

作者信息

Prokudina-Kantorovich E N, Semenova N P, Berezina O N, Moisiadi S A, Bektemirov T A

出版信息

Vopr Virusol. 1975 Sep-Oct(5):545-8.

Abstract

The structure of influenza virus virions from the standard and "Magnus" populations as well as intracellular syntheses induced by them were studied. Virions of influenza virus were shown to be heterogeneous with respect to the set of fragments in them. This heterogeneity was more marked in virions of the "Magnus" population and consisted in a relatively greater deficiency of large fragments. A marked induction of light RNA fractions in the cell by defective influenza virus was demonstrated. Synthesis of protein and the polypeptide composition of virions were found to be similiar in standard and "Magnus" viruses.

摘要

对来自标准毒株和“马格努斯”毒株群体的流感病毒颗粒结构以及它们所诱导的细胞内合成进行了研究。结果表明，流感病毒颗粒在其片段组成方面具有异质性。这种异质性在“马格努斯”毒株群体的病毒颗粒中更为明显，表现为大片段相对缺乏。已证实缺陷型流感病毒能显著诱导细胞内轻RNA组分的产生。发现标准毒株和“马格努斯”毒株的病毒颗粒在蛋白质合成和多肽组成方面相似。